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SMILES: COc1cccc(COc2cccc(c2)C#Cc2cccc(C)n2)c1

InChI Key: InChIKey=YGMOJLPJVYIQQJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160645   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50160645
PNG
(2-[3-(3-Methoxy-benzyloxy)-phenylethynyl]-6-methyl...)
Show SMILES COc1cccc(COc2cccc(c2)C#Cc2cccc(C)n2)c1
Show InChI InChI=1S/C22H19NO2/c1-17-6-3-9-20(23-17)13-12-18-7-4-11-22(14-18)25-16-19-8-5-10-21(15-19)24-2/h3-11,14-15H,16H2,1-2H3
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Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay

Bioorg Med Chem Lett 15: 945-9 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.047
BindingDB Entry DOI: 10.7270/Q2QN6681
More data for this
Ligand-Target Pair