BDBM50160648 3-(6-Methyl-pyridin-2-ylethynyl)-phenylamine::CHEMBL361339

SMILES: Cc1cccc(n1)C#Cc1cccc(N)c1

InChI Key: InChIKey=FGJHYEVFDNXSSV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160648   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50160648 (3-(6-Methyl-pyridin-2-ylethynyl)-phenylamine | CHE...) Show SMILES Cc1cccc(n1)C#Cc1cccc(N)c1 Show InChI InChI=1S/C14H12N2/c1-11-4-2-7-14(16-11)9-8-12-5-3-6-13(15)10-12/h2-7,10H,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
					More data for this Ligand-Target Pair