BDBM50160702 CHEMBL3787088

SMILES: CC(C)(C)NC(=O)C1N(Cc2cc(F)ccc2-c2ccccc2)C(=O)c2ccccc12

InChI Key: InChIKey=HFISOLFJBLJLHI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160702 (CHEMBL3787088) Show SMILES CC(C)(C)NC(=O)C1N(Cc2cc(F)ccc2-c2ccccc2)C(=O)c2ccccc12 Show InChI InChI=1S/C18H25Cl2N7O2S/c1-26-16(11-15(25-26)13-3-2-4-14(19)17(13)20)12-5-9-27(10-6-12)30(28,29)24-8-7-23-18(21)22/h2-4,11-12,24H,5-10H2,1H3,(H4,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50160702 (CHEMBL3787088) Show SMILES CC(C)(C)NC(=O)C1N(Cc2cc(F)ccc2-c2ccccc2)C(=O)c2ccccc12 Show InChI InChI=1S/C18H25Cl2N7O2S/c1-26-16(11-15(25-26)13-3-2-4-14(19)17(13)20)12-5-9-27(10-6-12)30(28,29)24-8-7-23-18(21)22/h2-4,11-12,24H,5-10H2,1H3,(H4,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160702 (CHEMBL3787088) Show SMILES CC(C)(C)NC(=O)C1N(Cc2cc(F)ccc2-c2ccccc2)C(=O)c2ccccc12 Show InChI InChI=1S/C18H25Cl2N7O2S/c1-26-16(11-15(25-26)13-3-2-4-14(19)17(13)20)12-5-9-27(10-6-12)30(28,29)24-8-7-23-18(21)22/h2-4,11-12,24H,5-10H2,1H3,(H4,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair