BDBM50160716 CHEMBL3785198

SMILES: CC(C)(CN1C(C(=O)NCCCC(F)F)c2ccccc2C1=O)c1ccc(F)cc1

InChI Key: InChIKey=ATDBDKQGCGVKBJ-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160716 (CHEMBL3785198) Show SMILES CC(C)(CN1C(C(=O)NCCCC(F)F)c2ccccc2C1=O)c1ccc(F)cc1 Show InChI InChI=1S/C25H36Cl2N8O2/c1-4-34(5-2)23(36)19(31-24(28)29)9-12-30-25(37)35-13-10-16(11-14-35)21-15-20(32-33(21)3)17-7-6-8-18(26)22(17)27/h6-8,15-16,19H,4-5,9-14H2,1-3H3,(H,30,37)(H4,28,29,31)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair