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SMILES: CN(C1CCN(CCCc2ccc(Cl)cc2)C1)C(=O)N1CCC(C1)N(C)C(=O)c1ccc(Oc2ccc(F)cc2)cc1

InChI Key: InChIKey=PVIPSFPLLZFEEP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160738   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50160738
PNG
(3-{[4-(4-Fluoro-phenoxy)-benzoyl]-methyl-amino}-py...)
Show SMILES CN(C1CCN(CCCc2ccc(Cl)cc2)C1)C(=O)N1CCC(C1)N(C)C(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C33H38ClFN4O3/c1-36(32(40)25-7-13-30(14-8-25)42-31-15-11-27(35)12-16-31)29-18-21-39(23-29)33(41)37(2)28-17-20-38(22-28)19-3-4-24-5-9-26(34)10-6-24/h5-16,28-29H,3-4,17-23H2,1-2H3
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PC cid
PC sid
UniChem
Article
PubMed
 5.30n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cells

Bioorg Med Chem Lett 15: 999-1004 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.036
BindingDB Entry DOI: 10.7270/Q21R6R9X
More data for this
Ligand-Target Pair