BDBM50160820 CHEMBL182708::Methanesulfonic acid (R)-3-{2-[(R)-2-(3-benzoylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester

SMILES: C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NC(=O)c2ccccc2)c1

InChI Key: InChIKey=WYTFAQBIDABWBM-KOSHJBKYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50160820 (CHEMBL182708 | Methanesulfonic acid (R)-3-{2-[(R)-...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C27H29N3O5S/c1-18(14-21-16-29-26-23(21)12-7-13-25(26)35-36(2,33)34)28-17-24(31)20-10-6-11-22(15-20)30-27(32)19-8-4-3-5-9-19/h3-13,15-16,18,24,28-29,31H,14,17H2,1-2H3,(H,30,32)/t18-,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was assessed by measuring cAMP accumulation in CHO cells expressing human beta-2 adrenergic receptor				Bioorg Med Chem Lett 15: 1061-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.033 BindingDB Entry DOI: 10.7270/Q2TD9WVK
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50160820 (CHEMBL182708 | Methanesulfonic acid (R)-3-{2-[(R)-...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C27H29N3O5S/c1-18(14-21-16-29-26-23(21)12-7-13-25(26)35-36(2,33)34)28-17-24(31)20-10-6-11-22(15-20)30-27(32)19-8-4-3-5-9-19/h3-13,15-16,18,24,28-29,31H,14,17H2,1-2H3,(H,30,32)/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was assessed by measuring cAMP accumulation in CHO cells expressing human beta-1 adrenergic receptor				Bioorg Med Chem Lett 15: 1061-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.033 BindingDB Entry DOI: 10.7270/Q2TD9WVK
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50160820 (CHEMBL182708 | Methanesulfonic acid (R)-3-{2-[(R)-...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C27H29N3O5S/c1-18(14-21-16-29-26-23(21)12-7-13-25(26)35-36(2,33)34)28-17-24(31)20-10-6-11-22(15-20)30-27(32)19-8-4-3-5-9-19/h3-13,15-16,18,24,28-29,31H,14,17H2,1-2H3,(H,30,32)/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was assessed by measuring cAMP accumulation in CHO cells expressing human beta-3 adrenergic receptor				Bioorg Med Chem Lett 15: 1061-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.033 BindingDB Entry DOI: 10.7270/Q2TD9WVK
					More data for this Ligand-Target Pair