BDBM50160822 CHEMBL362293::Methanesulfonic acid 3-{(R)-2-[(R)-2-(3-benzylamino-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yl ester

SMILES: C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NCc2ccccc2)c1

InChI Key: InChIKey=LGHCNFZLEQZRMA-CLOONOSVSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50160822 (CHEMBL362293 | Methanesulfonic acid 3-{(R)-2-[(R)-...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NCc2ccccc2)c1 Show InChI InChI=1S/C27H31N3O4S/c1-19(14-22-17-30-27-24(22)12-7-13-26(27)34-35(2,32)33)28-18-25(31)21-10-6-11-23(15-21)29-16-20-8-4-3-5-9-20/h3-13,15,17,19,25,28-31H,14,16,18H2,1-2H3/t19-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was assessed by measuring cAMP accumulation in CHO cells expressing human beta-3 adrenergic receptor				Bioorg Med Chem Lett 15: 1061-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.033 BindingDB Entry DOI: 10.7270/Q2TD9WVK
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50160822 (CHEMBL362293 | Methanesulfonic acid 3-{(R)-2-[(R)-...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(NCc2ccccc2)c1 Show InChI InChI=1S/C27H31N3O4S/c1-19(14-22-17-30-27-24(22)12-7-13-26(27)34-35(2,32)33)28-18-25(31)21-10-6-11-23(15-21)29-16-20-8-4-3-5-9-20/h3-13,15,17,19,25,28-31H,14,16,18H2,1-2H3/t19-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was assessed by measuring cAMP accumulation in CHO cells expressing human beta-2 adrenergic receptor				Bioorg Med Chem Lett 15: 1061-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.033 BindingDB Entry DOI: 10.7270/Q2TD9WVK
					More data for this Ligand-Target Pair