BDBM50160825 Benzenesulfonic acid 3-{(R)-1-hydroxy-2-[(R)-2-(7-methanesulfonyloxy-1H-indol-3-yl)-1-methyl-ethylamino]-ethyl}-phenyl ester::CHEMBL184584

SMILES: C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(OS(=O)(=O)c2ccccc2)c1

InChI Key: InChIKey=PGIVEOHZAMQLKP-KOSHJBKYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50160825 (Benzenesulfonic acid 3-{(R)-1-hydroxy-2-[(R)-2-(7-...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NC[C@H](O)c1cccc(OS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C26H28N2O7S2/c1-18(14-20-16-28-26-23(20)12-7-13-25(26)35-36(2,30)31)27-17-24(29)19-8-6-9-21(15-19)34-37(32,33)22-10-4-3-5-11-22/h3-13,15-16,18,24,27-29H,14,17H2,1-2H3/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was assessed by measuring cAMP accumulation in CHO cells expressing human beta-3 adrenergic receptor				Bioorg Med Chem Lett 15: 1061-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.033 BindingDB Entry DOI: 10.7270/Q2TD9WVK
					More data for this Ligand-Target Pair