BDBM50160857 1-Phenyl-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL178651

SMILES: O=C1CCC2(N1c1ccccc1)C(=O)NC(=O)NC2=O

InChI Key: InChIKey=XVIHAKHSIOBKFG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50160857 (1-Phenyl-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-te...) Show SMILES O=C1CCC2(N1c1ccccc1)C(=O)NC(=O)NC2=O Show InChI InChI=1S/C13H11N3O4/c17-9-6-7-13(10(18)14-12(20)15-11(13)19)16(9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H2,14,15,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 15: 1101-6 (2005) Article DOI: 10.1016/j.bmcl.2004.12.016 BindingDB Entry DOI: 10.7270/Q2F47NN2
					More data for this Ligand-Target Pair