BDBM50160926 3''-({[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-hexahydro-pyrrolo[1,2-c]imidazol-6-yl]-ethyl-amino}-methyl)-biphenyl-4-carbonitrile::CHEMBL182510

SMILES: CCN(Cc1cccc(c1)-c1ccc(cc1)C#N)[C@H]1Cc2c(O)n(-c3cc(Cl)cc(Cl)c3)c(=O)n2C1

InChI Key: InChIKey=IXUYPOXDQNNYKS-VWLOTQADSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160926 (3''-({[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-...) Show SMILES CCN(Cc1cccc(c1)-c1ccc(cc1)C#N)[C@H]1Cc2c(O)n(-c3cc(Cl)cc(Cl)c3)c(=O)n2C1 Show InChI InChI=1S/C28H24Cl2N4O2/c1-2-32(16-19-4-3-5-21(10-19)20-8-6-18(15-31)7-9-20)25-14-26-27(35)34(28(36)33(26)17-25)24-12-22(29)11-23(30)13-24/h3-13,25,35H,2,14,16-17H2,1H3/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
					More data for this Ligand-Target Pair