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SMILES: Cc1ccc(O)c(c1)C(=O)Nc1cccc(C)n1

InChI Key: InChIKey=WLXMZBWXBIVNKC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161017   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50161017
PNG
(2-Hydroxy-5-methyl-N-(6-methyl-pyridin-2-yl)-benza...)
Show SMILES Cc1ccc(O)c(c1)C(=O)Nc1cccc(C)n1
Show InChI InChI=1S/C14H14N2O2/c1-9-6-7-12(17)11(8-9)14(18)16-13-5-3-4-10(2)15-13/h3-8,17H,1-2H3,(H,15,16,18)
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n/an/a 105n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against human recombinant metabotropic glutamate receptor 5 (mGlu5) in Ltk cells determined using fluorescence detection met...

Bioorg Med Chem Lett 15: 1197-200 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.078
BindingDB Entry DOI: 10.7270/Q28G8K6P
More data for this
Ligand-Target Pair