BDBM50161265 CHEMBL3785255

SMILES: Fc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1

InChI Key: InChIKey=INQQFIRLBWFBMV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep))	BDBM50161265 (CHEMBL3785255) Show SMILES Fc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C24H20FN3O3/c25-19-11-13-20(14-12-19)26-21(29)15-16-28-22(30)24(27-23(28)31,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,29)(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...				Eur J Med Chem 115: 121-31 (2016) BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50161265 (CHEMBL3785255) Show SMILES Fc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C24H20FN3O3/c25-19-11-13-20(14-12-19)26-21(29)15-16-28-22(30)24(27-23(28)31,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,29)(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of ovine COX1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by enzyme immunoassay				Eur J Med Chem 115: 121-31 (2016) BindingDB Entry DOI: 10.7270/Q22N545K
					More data for this Ligand-Target Pair