BDBM50161353 CHEMBL3785596

SMILES: CN1CCN(Cc2cccc(NC(=O)Nc3cccc4C(=O)N5CCCCC5c34)n2)CC1

InChI Key: InChIKey=UZGUEHXKQYODMU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50161353 (CHEMBL3785596) Show SMILES CN1CCN(Cc2cccc(NC(=O)Nc3cccc4C(=O)N5CCCCC5c34)n2)CC1 Show InChI InChI=1S/C17H15N3O/c1-9-3-5-11-8-13-15(12(11)7-9)19-17(18)20-16(13)14-6-4-10(2)21-14/h3-7H,8H2,1-2H3,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of GST fused human recombinant DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by scintillation counting in...				Eur J Med Chem 115: 311-25 (2016) BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair