BDBM50161427 1-[4-(4-Methoxy-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181230

SMILES: COc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)Cc2ccccc2C)cc1

InChI Key: InChIKey=OZIPSESMEGJVGY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161427 (1-[4-(4-Methoxy-benzyl)-[1,4'']bipiperidinyl-1''-y...) Show SMILES COc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)Cc2ccccc2C)cc1 Show InChI InChI=1S/C27H36N2O2/c1-21-5-3-4-6-24(21)20-27(30)29-17-13-25(14-18-29)28-15-11-23(12-16-28)19-22-7-9-26(31-2)10-8-22/h3-10,23,25H,11-20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	792	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair