BDBM50161428 CHEMBL362401::N-[(3R,4S)-4-(3,4-Dichloro-benzyl)-1''-(quinoline-6-carbonyl)-[1,4'']bipiperidinyl-3-ylmethyl]-acetamide

SMILES: CC(=O)NC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1

InChI Key: InChIKey=YXKQDJSENLLDCP-RCZVLFRGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161428 (CHEMBL362401 | N-[(3R,4S)-4-(3,4-Dichloro-benzyl)-...) Show SMILES CC(=O)NC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 Show InChI InChI=1S/C30H34Cl2N4O2/c1-20(37)34-18-25-19-36(12-8-22(25)15-21-4-6-27(31)28(32)16-21)26-9-13-35(14-10-26)30(38)24-5-7-29-23(17-24)3-2-11-33-29/h2-7,11,16-17,22,25-26H,8-10,12-15,18-19H2,1H3,(H,34,37)/t22-,25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
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