BDBM50161436 CHEMBL178438::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxymethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone

SMILES: COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1

InChI Key: InChIKey=NIBJOLRGYNXOPG-QPPBQGQZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161436 (CHEMBL178438 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...) Show SMILES COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 Show InChI InChI=1S/C29H33Cl2N3O2/c1-36-19-24-18-34(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-33(14-10-25)29(35)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25H,8-10,12-15,18-19H2,1H3/t21-,24+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161436 (CHEMBL178438 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...) Show SMILES COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 Show InChI InChI=1S/C29H33Cl2N3O2/c1-36-19-24-18-34(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-33(14-10-25)29(35)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25H,8-10,12-15,18-19H2,1H3/t21-,24+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair