BDBM50161444 1-[4-(3-Chloro-5-fluoro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181794

SMILES: Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cc(F)cc(Cl)c2)CC1

InChI Key: InChIKey=CJVAFNHVSYHRHI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161444 (1-[4-(3-Chloro-5-fluoro-benzyl)-[1,4'']bipiperidin...) Show SMILES Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cc(F)cc(Cl)c2)CC1 Show InChI InChI=1S/C26H32ClFN2O/c1-19-4-2-3-5-22(19)17-26(31)30-12-8-25(9-13-30)29-10-6-20(7-11-29)14-21-15-23(27)18-24(28)16-21/h2-5,15-16,18,20,25H,6-14,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	504	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair