BDBM50161450 CHEMBL425875::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-(1H-indol-4-yl)-methanone

SMILES: Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3[nH]ccc23)cc1Cl

InChI Key: InChIKey=NGGMBNXWWMYHCB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161450 (CHEMBL425875 | [4-(3,4-Dichloro-benzyl)-[1,4'']bip...) Show SMILES Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3[nH]ccc23)cc1Cl Show InChI InChI=1S/C26H29Cl2N3O/c27-23-5-4-19(17-24(23)28)16-18-7-12-30(13-8-18)20-9-14-31(15-10-20)26(32)22-2-1-3-25-21(22)6-11-29-25/h1-6,11,17-18,20,29H,7-10,12-16H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair