BDBM50161811 CHEMBL3785615

SMILES: Cc1ccc(Nc2nc(N)nc(COC(=O)c3cnc4ccccc4n3)n2)cc1

InChI Key: InChIKey=DPTLRVMBLVQLPN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50161811 (CHEMBL3785615) Show SMILES Cc1ccc(Nc2nc(N)nc(COC(=O)c3cnc4ccccc4n3)n2)cc1 Show InChI InChI=1S/C20H17N7O2/c1-12-6-8-13(9-7-12)23-20-26-17(25-19(21)27-20)11-29-18(28)16-10-22-14-4-2-3-5-15(14)24-16/h2-10H,11H2,1H3,(H3,21,23,25,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase using 234-nt long RNA/18-mer DNA oligonucleotide as template/primer preincubated for 15 mins followed by inc...				Bioorg Med Chem 24: 2519-29 (2016) BindingDB Entry DOI: 10.7270/Q2NC632Q
					More data for this Ligand-Target Pair