BDBM50161814 CHEMBL3786457

SMILES: Cc1ccccc1Nc1nc(Cn2ccc(cc2=O)C(F)(F)F)nc(=N)[nH]1

InChI Key: InChIKey=WEAAUXZTXHZCHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50161814 (CHEMBL3786457) Show SMILES Cc1ccccc1Nc1nc(Cn2ccc(cc2=O)C(F)(F)F)nc(=N)[nH]1 Show InChI InChI=1S/C17H15F3N6O/c1-10-4-2-3-5-12(10)22-16-24-13(23-15(21)25-16)9-26-7-6-11(8-14(26)27)17(18,19)20/h2-8H,9H2,1H3,(H3,21,22,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase using 234-nt long RNA/18-mer DNA oligonucleotide as template/primer preincubated for 15 mins followed by inc...				Bioorg Med Chem 24: 2519-29 (2016) BindingDB Entry DOI: 10.7270/Q2NC632Q
					More data for this Ligand-Target Pair