BDBM50162040 (R)-1-(2-fluorobenzyl)-3-(2-amino-2-phenylethyl)-5-(2-fluorophenyl)-6-methylpyrimidine-2,4(1H,3H)-dione::3-((R)-2-Amino-2-phenyl-ethyl)-1-(2-fluoro-benzyl)-5-(2-fluoro-phenyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL361798

SMILES: Cc1c(-c2ccccc2F)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1ccccc1F

InChI Key: InChIKey=JZCXQHIICPFYHI-QHCPKHFHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50162040 ((R)-1-(2-fluorobenzyl)-3-(2-amino-2-phenylethyl)-5...) Show SMILES Cc1c(-c2ccccc2F)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1ccccc1F |r,wD:14.15,(-.33,-43.25,;-1.67,-42.48,;-1.67,-40.94,;-.33,-40.17,;1,-40.94,;2.33,-40.17,;2.33,-38.63,;.98,-37.86,;-.34,-38.63,;-1.68,-37.87,;-3,-40.16,;-3,-38.62,;-4.32,-40.94,;-5.66,-40.17,;-6.99,-40.95,;-6.99,-42.49,;-8.32,-40.18,;-8.33,-38.64,;-9.66,-37.87,;-10.99,-38.65,;-10.98,-40.2,;-9.65,-40.96,;-4.32,-42.48,;-5.66,-43.25,;-3,-43.24,;-3,-44.78,;-1.66,-45.55,;-1.67,-47.09,;-.34,-47.86,;1,-47.09,;.99,-45.54,;-.34,-44.78,;-1.68,-44.01,)| Show InChI InChI=1S/C26H23F2N3O2/c1-17-24(20-12-6-8-14-22(20)28)25(32)31(16-23(29)18-9-3-2-4-10-18)26(33)30(17)15-19-11-5-7-13-21(19)27/h2-14,23H,15-16,29H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
					More data for this Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50162040 ((R)-1-(2-fluorobenzyl)-3-(2-amino-2-phenylethyl)-5...) Show SMILES Cc1c(-c2ccccc2F)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1ccccc1F |r,wD:14.15,(-.33,-43.25,;-1.67,-42.48,;-1.67,-40.94,;-.33,-40.17,;1,-40.94,;2.33,-40.17,;2.33,-38.63,;.98,-37.86,;-.34,-38.63,;-1.68,-37.87,;-3,-40.16,;-3,-38.62,;-4.32,-40.94,;-5.66,-40.17,;-6.99,-40.95,;-6.99,-42.49,;-8.32,-40.18,;-8.33,-38.64,;-9.66,-37.87,;-10.99,-38.65,;-10.98,-40.2,;-9.65,-40.96,;-4.32,-42.48,;-5.66,-43.25,;-3,-43.24,;-3,-44.78,;-1.66,-45.55,;-1.67,-47.09,;-.34,-47.86,;1,-47.09,;.99,-45.54,;-.34,-44.78,;-1.68,-44.01,)| Show InChI InChI=1S/C26H23F2N3O2/c1-17-24(20-12-6-8-14-22(20)28)25(32)31(16-23(29)18-9-3-2-4-10-18)26(33)30(17)15-19-11-5-7-13-21(19)27/h2-14,23H,15-16,29H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for Human gonadotropin-releasing hormone receptor				J Med Chem 48: 1169-78 (2005) Article DOI: 10.1021/jm049218c BindingDB Entry DOI: 10.7270/Q2MK6CD8
					More data for this Ligand-Target Pair