BDBM50162369 CHEMBL195081::[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(3,5-dimethyl-phenyl)-ethyl]-amine

SMILES: Cc1cc(C)cc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1

InChI Key: InChIKey=JYXNBOOVPKYADN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50162369 (CHEMBL195081 | [2-Biphenyl-4-yl-2-(4-cyclohexyl-pi...) Show SMILES Cc1cc(C)cc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C34H45N3/c1-27-23-28(2)25-29(24-27)17-18-35-26-34(32-15-13-31(14-16-32)30-9-5-3-6-10-30)37-21-19-36(20-22-37)33-11-7-4-8-12-33/h3,5-6,9-10,13-16,23-25,33-35H,4,7-8,11-12,17-22,26H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	517	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biographics Laboratory 3R Curated by ChEMBL					Assay Description Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)				J Med Chem 48: 1515-27 (2005) Article DOI: 10.1021/jm040827u BindingDB Entry DOI: 10.7270/Q2KK9B8W
					More data for this Ligand-Target Pair