BDBM50162549 7-Chloro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)-3H-quinazolin-4-one::CHEMBL178442

SMILES: Oc1ccccc1-c1nc2cc(Cl)ccc2c(=O)n1CCc1cccc(F)c1

InChI Key: InChIKey=KNIMOPDLGMIJCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50162549 (7-Chloro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...) Show SMILES Oc1ccccc1-c1nc2cc(Cl)ccc2c(=O)n1CCc1cccc(F)c1 Show InChI InChI=1S/C22H16ClFN2O2/c23-15-8-9-17-19(13-15)25-21(18-6-1-2-7-20(18)27)26(22(17)28)11-10-14-4-3-5-16(24)12-14/h1-9,12-13,27H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair