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BDBM50162566 6,7-Dichloro-2-propyl-5-[4-(2H-tetrazol-5-yl)-benzyloxy]-indan-1-one::CHEMBL183541

SMILES: CCCC1Cc2cc(OCc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O

InChI Key: InChIKey=TXMQCTWFGCLXEB-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162566   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50162566
PNG
(6,7-Dichloro-2-propyl-5-[4-(2H-tetrazol-5-yl)-benz...)
Show SMILES CCCC1Cc2cc(OCc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O
Show InChI InChI=1S/C20H18Cl2N4O2/c1-2-3-13-8-14-9-15(17(21)18(22)16(14)19(13)27)28-10-11-4-6-12(7-5-11)20-23-25-26-24-20/h4-7,9,13H,2-3,8,10H2,1H3,(H,23,24,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 282n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against metabotropic glutamate receptor 2


Bioorg Med Chem Lett 15: 1565-71 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.077
BindingDB Entry DOI: 10.7270/Q2XW4JBK
More data for this
Ligand-Target Pair