BDBM50162882 3-(1H-Imidazol-4-yl)-3-[(4-phenoxy-benzyl)-(4-phenyl-butyl)-amino]-propionic acid::CHEMBL361521

SMILES: OC(=O)CC(N(CCCCc1ccccc1)Cc1ccc(Oc2ccccc2)cc1)c1cnc[nH]1

InChI Key: InChIKey=MARYRVHUZOQJMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50162882 (3-(1H-Imidazol-4-yl)-3-[(4-phenoxy-benzyl)-(4-phen...) Show SMILES OC(=O)CC(N(CCCCc1ccccc1)Cc1ccc(Oc2ccccc2)cc1)c1cnc[nH]1 Show InChI InChI=1S/C29H31N3O3/c33-29(34)19-28(27-20-30-22-31-27)32(18-8-7-11-23-9-3-1-4-10-23)21-24-14-16-26(17-15-24)35-25-12-5-2-6-13-25/h1-6,9-10,12-17,20,22,28H,7-8,11,18-19,21H2,(H,30,31)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by ChEMBL					Assay Description Inhibition of Geranylgeranyl transferase type I				Bioorg Med Chem Lett 15: 1713-9 (2005) Article DOI: 10.1016/j.bmcl.2005.01.042 BindingDB Entry DOI: 10.7270/Q24F1Q7J
					More data for this Ligand-Target Pair