BDBM50162954 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]pyrrolo[1,2-a]azepine::CHEMBL179557

SMILES: CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12

InChI Key: InChIKey=DZDAGFDMUXEPPJ-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50162954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50162954 (8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12 |t:8| Show InChI InChI=1S/C18H20ClN3/c1-20-7-9-21(10-8-20)18-12-15-11-16(19)5-4-14(15)13-22-6-2-3-17(18)22/h2-6,11-12H,7-10,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-ketanserin binding to rat 5-hydroxytryptamine 2A receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50162954 (8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12 |t:8| Show InChI InChI=1S/C18H20ClN3/c1-20-7-9-21(10-8-20)18-12-15-11-16(19)5-4-14(15)13-22-6-2-3-17(18)22/h2-6,11-12H,7-10,13H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-mesulergine bindng to rat 5-hydroxytryptamine 2C receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50162954 (8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12 |t:8| Show InChI InChI=1S/C18H20ClN3/c1-20-7-9-21(10-8-20)18-12-15-11-16(19)5-4-14(15)13-22-6-2-3-17(18)22/h2-6,11-12H,7-10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-7-OH-DPAT binding to Dopamine D3 receptor expressed in Sf9 cells				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50162954 (8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12 |t:8| Show InChI InChI=1S/C18H20ClN3/c1-20-7-9-21(10-8-20)18-12-15-11-16(19)5-4-14(15)13-22-6-2-3-17(18)22/h2-6,11-12H,7-10,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-SCH- 23390 binding to rat dopamine D1 receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50162954 (8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12 |t:8| Show InChI InChI=1S/C18H20ClN3/c1-20-7-9-21(10-8-20)18-12-15-11-16(19)5-4-14(15)13-22-6-2-3-17(18)22/h2-6,11-12H,7-10,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-spiperone binding to rat dopamine D2 receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair