BDBM50162955 3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]pyrrolo[1,2-a]azepine::CHEMBL178564

SMILES: CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12

InChI Key: InChIKey=KCHOGJMXHYZZSG-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50162955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50162955 (3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12 |t:8| Show InChI InChI=1S/C19H23N3/c1-15-7-8-18-19(21-11-9-20(2)10-12-21)13-16-5-3-4-6-17(16)14-22(15)18/h3-8,13H,9-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-ketanserin binding to rat 5-hydroxytryptamine 2A receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50162955 (3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12 |t:8| Show InChI InChI=1S/C19H23N3/c1-15-7-8-18-19(21-11-9-20(2)10-12-21)13-16-5-3-4-6-17(16)14-22(15)18/h3-8,13H,9-12,14H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-mesulergine bindng to rat 5-hydroxytryptamine 2C receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50162955 (3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12 |t:8| Show InChI InChI=1S/C19H23N3/c1-15-7-8-18-19(21-11-9-20(2)10-12-21)13-16-5-3-4-6-17(16)14-22(15)18/h3-8,13H,9-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-7-OH-DPAT binding to Dopamine D3 receptor expressed in Sf9 cells				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50162955 (3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12 |t:8| Show InChI InChI=1S/C19H23N3/c1-15-7-8-18-19(21-11-9-20(2)10-12-21)13-16-5-3-4-6-17(16)14-22(15)18/h3-8,13H,9-12,14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-SCH- 23390 binding to rat dopamine D1 receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50162955 (3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]p...) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12 |t:8| Show InChI InChI=1S/C19H23N3/c1-15-7-8-18-19(21-11-9-20(2)10-12-21)13-16-5-3-4-6-17(16)14-22(15)18/h3-8,13H,9-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	923	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]-spiperone binding to rat dopamine D2 receptor				J Med Chem 48: 1705-8 (2005) Article DOI: 10.1021/jm049629t BindingDB Entry DOI: 10.7270/Q2R49Q72
					More data for this Ligand-Target Pair