BDBM50163043 1-[1-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonyl)-piperidin-4-yl]-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL176258

SMILES: Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N1CCC(CC1)N1C(=O)OCc2ccccc12

InChI Key: InChIKey=KJBRZKGIDGZCRK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163043   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163043 (1-[1-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfon...) Show SMILES Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N1CCC(CC1)N1C(=O)OCc2ccccc12 Show InChI InChI=1S/C22H21ClN2O4S2/c1-14-18-12-16(23)6-7-20(18)30-21(14)31(27,28)24-10-8-17(9-11-24)25-19-5-3-2-4-15(19)13-29-22(25)26/h2-7,12,17H,8-11,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair