BDBM50163048 5-Chloro-thiophene-2-sulfonic acid [3-(1-methyl-piperidin-4-yl)-1H-indol-5-yl]-amide::CHEMBL367730

SMILES: CN1CCC(CC1)c1c[nH]c2ccc(NS(=O)(=O)c3ccc(Cl)s3)cc12

InChI Key: InChIKey=IXFIZZJAUYTVFQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163048 (5-Chloro-thiophene-2-sulfonic acid [3-(1-methyl-pi...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NS(=O)(=O)c3ccc(Cl)s3)cc12 Show InChI InChI=1S/C18H20ClN3O2S2/c1-22-8-6-12(7-9-22)15-11-20-16-3-2-13(10-14(15)16)21-26(23,24)18-5-4-17(19)25-18/h2-5,10-12,20-21H,6-9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	24.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair