BDBM50163086 CHEMBL427134::Naphthalene-2-sulfonic acid [3-(2-pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-amide

SMILES: O=S(=O)(Nc1ccc2[nH]cc(CCN3CCCC3)c2c1)c1ccc2ccccc2c1

InChI Key: InChIKey=WWJUEGBQBBZAGT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163086 (CHEMBL427134 | Naphthalene-2-sulfonic acid [3-(2-p...) Show SMILES O=S(=O)(Nc1ccc2[nH]cc(CCN3CCCC3)c2c1)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H25N3O2S/c28-30(29,22-9-7-18-5-1-2-6-19(18)15-22)26-21-8-10-24-23(16-21)20(17-25-24)11-14-27-12-3-4-13-27/h1-2,5-10,15-17,25-26H,3-4,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair