BDBM50163087 1-[1-(Naphthalene-1-sulfonyl)-piperidin-4-yl]-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL179034

SMILES: O=C1OCc2ccccc2N1C1CCN(CC1)S(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=TYYXFZFUUWYFQO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163087 (1-[1-(Naphthalene-1-sulfonyl)-piperidin-4-yl]-1,4-...) Show SMILES O=C1OCc2ccccc2N1C1CCN(CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N2O4S/c26-23-25(21-10-4-2-7-18(21)16-29-23)19-12-14-24(15-13-19)30(27,28)22-11-5-8-17-6-1-3-9-20(17)22/h1-11,19H,12-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	51.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair