BDBM50163100 6-Chloro-imidazo[2,1-b]thiazole-5-sulfonic acid [1-(2-piperidin-1-yl-ethyl)-1H-indol-5-yl]-amide::CHEMBL367305

SMILES: Clc1nc2sccn2c1S(=O)(=O)Nc1ccc2n(CCN3CCCCC3)ccc2c1

InChI Key: InChIKey=VRGJFPLLFDBSMA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163100 (6-Chloro-imidazo[2,1-b]thiazole-5-sulfonic acid [1...) Show SMILES Clc1nc2sccn2c1S(=O)(=O)Nc1ccc2n(CCN3CCCCC3)ccc2c1 Show InChI InChI=1S/C20H22ClN5O2S2/c21-18-19(26-12-13-29-20(26)22-18)30(27,28)23-16-4-5-17-15(14-16)6-9-25(17)11-10-24-7-2-1-3-8-24/h4-6,9,12-14,23H,1-3,7-8,10-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair