BDBM50163252 2-Biphenyl-4-yl-1H-benzoimidazole-5-carboxylic acid amide::CHEMBL193476

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=VXAXNRIWBUPKJB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163252 (2-Biphenyl-4-yl-1H-benzoimidazole-5-carboxylic aci...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O/c21-19(24)16-10-11-17-18(12-16)23-20(22-17)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H2,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair