BDBM50163256 2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxylic acid methylamide::CHEMBL179636

SMILES: CNC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=ULODUALKWCAZLZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163256 (2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...) Show SMILES CNC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C21H17N3O2/c1-22-21(25)15-9-12-18-19(13-15)24-20(23-18)14-7-10-17(11-8-14)26-16-5-3-2-4-6-16/h2-13H,1H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair