BDBM50163272 3-[4-(5-Carbamoyl-1H-benzoimidazol-2-yl)-phenoxy]-benzoic acid::CHEMBL381436

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2cccc(c2)C(O)=O)cc1

InChI Key: InChIKey=PMRXAXHHFVVMHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163272 (3-[4-(5-Carbamoyl-1H-benzoimidazol-2-yl)-phenoxy]-...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C21H15N3O4/c22-19(25)13-6-9-17-18(11-13)24-20(23-17)12-4-7-15(8-5-12)28-16-3-1-2-14(10-16)21(26)27/h1-11H,(H2,22,25)(H,23,24)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair