BDBM50163358 CHEMBL3793411

SMILES: Cc1c2COC(=O)c2ccc1CCN1CCN(CC1)C(=O)Cc1cncc(c1)-n1cnnn1

InChI Key: InChIKey=FZCPIQKWQVHTPN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50163358 (CHEMBL3793411) Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CC1)C(=O)Cc1cncc(c1)-n1cnnn1 Show InChI InChI=1S/C23H25N7O3/c1-16-18(2-3-20-21(16)14-33-23(20)32)4-5-28-6-8-29(9-7-28)22(31)11-17-10-19(13-24-12-17)30-15-25-26-27-30/h2-3,10,12-13,15H,4-9,11,14H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 26: 2339-43 (2016) BindingDB Entry DOI: 10.7270/Q2668G3Q
					More data for this Ligand-Target Pair
Renal Outer Medullary Potassium (ROMK) (Rattus norvegicus (Rat))	BDBM50163358 (CHEMBL3793411) Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CC1)C(=O)Cc1cncc(c1)-n1cnnn1 Show InChI InChI=1S/C23H25N7O3/c1-16-18(2-3-20-21(16)14-33-23(20)32)4-5-28-6-8-29(9-7-28)22(31)11-17-10-19(13-24-12-17)30-15-25-26-27-30/h2-3,10,12-13,15H,4-9,11,14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assay				Bioorg Med Chem Lett 26: 2339-43 (2016) BindingDB Entry DOI: 10.7270/Q2668G3Q
					More data for this Ligand-Target Pair