null

SMILES: COC(CN1CCN(CC1)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C

InChI Key: InChIKey=ISRDPDAMWUGJKM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM50163362 (CHEMBL3792808) Show SMILES COC(CN1CCN(CC1)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C Show InChI InChI=1S/C24H27N7O4/c1-16-18(4-5-19-20(16)14-35-24(19)33)21(34-2)13-29-7-9-30(10-8-29)23(32)11-17-3-6-22(25-12-17)31-15-26-27-28-31/h3-6,12,15,21H,7-11,13-14H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 26: 2339-43 (2016) Article DOI: 10.1016/j.bmcl.2016.03.035 BindingDB Entry DOI: 10.7270/Q2668G3Q
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM50163362 (CHEMBL3792808) Show SMILES COC(CN1CCN(CC1)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C Show InChI InChI=1S/C24H27N7O4/c1-16-18(4-5-19-20(16)14-35-24(19)33)21(34-2)13-29-7-9-30(10-8-29)23(32)11-17-3-6-22(25-12-17)31-15-26-27-28-31/h3-6,12,15,21H,7-11,13-14H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assay				Bioorg Med Chem Lett 26: 2339-43 (2016) Article DOI: 10.1016/j.bmcl.2016.03.035 BindingDB Entry DOI: 10.7270/Q2668G3Q
					More data for this Ligand-Target Pair