BDBM50163365 CHEMBL3794249

SMILES: O=C(Cc1ccc(cc1)-n1cnnn1)N1CC2C(CCc3ccc4C(=O)OCc4c3)C2C1

InChI Key: InChIKey=YJUTZQFCPHUDLY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renal Outer Medullary Potassium (ROMK) (Rattus norvegicus (Rat))	BDBM50163365 (CHEMBL3794249) Show SMILES O=C(Cc1ccc(cc1)-n1cnnn1)N1CC2C(CCc3ccc4C(=O)OCc4c3)C2C1 Show InChI InChI=1S/C24H23N5O3/c30-23(10-16-1-5-18(6-2-16)29-14-25-26-27-29)28-11-21-20(22(21)12-28)8-4-15-3-7-19-17(9-15)13-32-24(19)31/h1-3,5-7,9,14,20-22H,4,8,10-13H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assay				Bioorg Med Chem Lett 26: 2339-43 (2016) BindingDB Entry DOI: 10.7270/Q2668G3Q
					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50163365 (CHEMBL3794249) Show SMILES O=C(Cc1ccc(cc1)-n1cnnn1)N1CC2C(CCc3ccc4C(=O)OCc4c3)C2C1 Show InChI InChI=1S/C24H23N5O3/c30-23(10-16-1-5-18(6-2-16)29-14-25-26-27-29)28-11-21-20(22(21)12-28)8-4-15-3-7-19-17(9-15)13-32-24(19)31/h1-3,5-7,9,14,20-22H,4,8,10-13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-MK499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 26: 2339-43 (2016) BindingDB Entry DOI: 10.7270/Q2668G3Q
					More data for this Ligand-Target Pair