BDBM50163638 1-(3-Acetyl-phenyl)-3-[2-(4-fluoro-benzyl)-piperidin-1-yl]-urea::CHEMBL368683

SMILES: CC(=O)c1cccc(NC(=O)NN2CCCCC2Cc2ccc(F)cc2)c1

InChI Key: InChIKey=SOEZEWJTMGDYDZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50163638 (1-(3-Acetyl-phenyl)-3-[2-(4-fluoro-benzyl)-piperid...) Show SMILES CC(=O)c1cccc(NC(=O)NN2CCCCC2Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C21H24FN3O2/c1-15(26)17-5-4-6-19(14-17)23-21(27)24-25-12-3-2-7-20(25)13-16-8-10-18(22)11-9-16/h4-6,8-11,14,20H,2-3,7,12-13H2,1H3,(H2,23,24,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of eotaxin-induced chemotaxis of human eosinophils				J Med Chem 48: 2194-211 (2005) Article DOI: 10.1021/jm049530m BindingDB Entry DOI: 10.7270/Q2XP74F1
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50163638 (1-(3-Acetyl-phenyl)-3-[2-(4-fluoro-benzyl)-piperid...) Show SMILES CC(=O)c1cccc(NC(=O)NN2CCCCC2Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C21H24FN3O2/c1-15(26)17-5-4-6-19(14-17)23-21(27)24-25-12-3-2-7-20(25)13-16-8-10-18(22)11-9-16/h4-6,8-11,14,20H,2-3,7,12-13H2,1H3,(H2,23,24,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cells				J Med Chem 48: 2194-211 (2005) Article DOI: 10.1021/jm049530m BindingDB Entry DOI: 10.7270/Q2XP74F1
					More data for this Ligand-Target Pair