BDBM50163803 5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrazol-1-yl-phenoxy)-phenoxy]-piperidine-2,4,6-trione::CHEMBL180900

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)-n3cccn3)cc2)C(=O)NC(=O)C(N)C1=O

InChI Key: InChIKey=LZYKHUZBVFGWCA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50163803 (5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrazol-1-yl-ph...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-n3cccn3)cc2)C(=O)NC(=O)C(N)C1=O Show InChI InChI=1S/C24H24N4O6/c1-2-32-15-12-24(21(29)20(25)22(30)27-23(24)31)34-19-10-8-18(9-11-19)33-17-6-4-16(5-7-17)28-14-3-13-26-28/h3-11,13-14,20H,2,12,15,25H2,1H3,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against matrix metalloprotease 13				Bioorg Med Chem Lett 15: 1807-10 (2005) Article DOI: 10.1016/j.bmcl.2005.02.038 BindingDB Entry DOI: 10.7270/Q2JH3KPW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50163803 (5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrazol-1-yl-ph...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-n3cccn3)cc2)C(=O)NC(=O)C(N)C1=O Show InChI InChI=1S/C24H24N4O6/c1-2-32-15-12-24(21(29)20(25)22(30)27-23(24)31)34-19-10-8-18(9-11-19)33-17-6-4-16(5-7-17)28-14-3-13-26-28/h3-11,13-14,20H,2,12,15,25H2,1H3,(H,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against matrix metalloprotease 14				Bioorg Med Chem Lett 15: 1807-10 (2005) Article DOI: 10.1016/j.bmcl.2005.02.038 BindingDB Entry DOI: 10.7270/Q2JH3KPW
					More data for this Ligand-Target Pair