BDBM50163819 5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-2-yl-phenoxy)-phenoxy]-piperidine-2,4,6-trione::CHEMBL361783

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nccs3)cc2)C(=O)NC(=O)C(N)C1=O

InChI Key: InChIKey=FQEZYKOXVAISOF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50163819 (5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-2-yl-ph...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nccs3)cc2)C(=O)NC(=O)C(N)C1=O Show InChI InChI=1S/C24H23N3O6S/c1-2-31-13-11-24(20(28)19(25)21(29)27-23(24)30)33-18-9-7-17(8-10-18)32-16-5-3-15(4-6-16)22-26-12-14-34-22/h3-10,12,14,19H,2,11,13,25H2,1H3,(H,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against matrix metalloprotease 13				Bioorg Med Chem Lett 15: 1807-10 (2005) Article DOI: 10.1016/j.bmcl.2005.02.038 BindingDB Entry DOI: 10.7270/Q2JH3KPW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14) (Homo sapiens (Human))	BDBM50163819 (5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-2-yl-ph...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nccs3)cc2)C(=O)NC(=O)C(N)C1=O Show InChI InChI=1S/C24H23N3O6S/c1-2-31-13-11-24(20(28)19(25)21(29)27-23(24)30)33-18-9-7-17(8-10-18)32-16-5-3-15(4-6-16)22-26-12-14-34-22/h3-10,12,14,19H,2,11,13,25H2,1H3,(H,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against matrix metalloprotease 14				Bioorg Med Chem Lett 15: 1807-10 (2005) Article DOI: 10.1016/j.bmcl.2005.02.038 BindingDB Entry DOI: 10.7270/Q2JH3KPW
					More data for this Ligand-Target Pair