BDBM50163899 CHEMBL183122::N-[3,5-Dichloro-4-(3-isopropyl-1H-indol-5-yloxy)-phenyl]-oxalamic acid methyl ester

SMILES: COC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(Cl)c1

InChI Key: InChIKey=CCTYHQGZHMQRSN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor (TR-alpha)/(TR-beta) (Homo sapiens (Human))	BDBM50163899 (CHEMBL183122 | N-[3,5-Dichloro-4-(3-isopropyl-1H-i...) Show SMILES COC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(Cl)c1 Show InChI InChI=1S/C20H18Cl2N2O4/c1-10(2)14-9-23-17-5-4-12(8-13(14)17)28-18-15(21)6-11(7-16(18)22)24-19(25)20(26)27-3/h4-10,23H,1-3H3,(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells				Bioorg Med Chem Lett 15: 1835-40 (2005) Article DOI: 10.1016/j.bmcl.2005.02.028 BindingDB Entry DOI: 10.7270/Q290239F
					More data for this Ligand-Target Pair