BDBM50163906 CHEMBL361162::[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-trifluoromethyl-phenyl]-acetic acid

SMILES: CC(C)c1c[nH]c2ccc(Oc3c(cc(CC(O)=O)cc3C(F)(F)F)C(F)(F)F)cc12

InChI Key: InChIKey=CEEMAUWOXPURCO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor (TR-alpha)/(TR-beta) (Homo sapiens (Human))	BDBM50163906 (CHEMBL361162 | [4-(3-Isopropyl-1H-indol-5-yloxy)-3...) Show SMILES CC(C)c1c[nH]c2ccc(Oc3c(cc(CC(O)=O)cc3C(F)(F)F)C(F)(F)F)cc12 Show InChI InChI=1S/C21H17F6NO3/c1-10(2)14-9-28-17-4-3-12(8-13(14)17)31-19-15(20(22,23)24)5-11(7-18(29)30)6-16(19)21(25,26)27/h3-6,8-10,28H,7H2,1-2H3,(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Agonist activity towards thyroid hormone receptor expressed in human HepG2 cells				Bioorg Med Chem Lett 15: 1835-40 (2005) Article DOI: 10.1016/j.bmcl.2005.02.028 BindingDB Entry DOI: 10.7270/Q290239F
					More data for this Ligand-Target Pair