BDBM50164010 CHEMBL182351::{Benzenesulfonyl-[6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-amino}-acetic acid tert-butyl ester

SMILES: Cn1cncc1CN1CC(Cc2cc(ccc12)C#N)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=BOAHFXYLVJDDQK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50164010 (CHEMBL182351 | {Benzenesulfonyl-[6-cyano-1-(3-meth...) Show SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)C#N)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H31N5O4S/c1-27(2,3)36-26(33)18-32(37(34,35)24-8-6-5-7-9-24)22-13-21-12-20(14-28)10-11-25(21)31(16-22)17-23-15-29-19-30(23)4/h5-12,15,19,22H,13,16-18H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human farnesyltransferase				Bioorg Med Chem Lett 15: 1895-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.004 BindingDB Entry DOI: 10.7270/Q2RB75CJ
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