BDBM50164027 1-Methyl-1H-pyrazole-4-sulfonic acid [6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-thiophen-3-ylmethyl-amide::CHEMBL362475

SMILES: Cn1cc(cn1)S(=O)(=O)N(Cc1ccsc1)C1CN(Cc2cncn2C)c2ccc(cc2C1)C#N

InChI Key: InChIKey=KVCBEZWLSRNJTD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50164027 (1-Methyl-1H-pyrazole-4-sulfonic acid [6-cyano-1-(3...) Show SMILES Cn1cc(cn1)S(=O)(=O)N(Cc1ccsc1)C1CN(Cc2cncn2C)c2ccc(cc2C1)C#N Show InChI InChI=1S/C24H25N7O2S2/c1-28-17-26-10-22(28)14-30-13-21(8-20-7-18(9-25)3-4-24(20)30)31(12-19-5-6-34-16-19)35(32,33)23-11-27-29(2)15-23/h3-7,10-11,15-17,21H,8,12-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human farnesyltransferase				Bioorg Med Chem Lett 15: 1895-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.004 BindingDB Entry DOI: 10.7270/Q2RB75CJ
					More data for this Ligand-Target Pair