BDBM50164074 (1S,2S)-Cyclopentane-1,2-dicarboxylic acid 1-[(1-[2,2'']bithiophenyl-5-yl-ethyl)-amide] 2-[methyl-(2''-sulfamoyl-biphenyl-4-ylmethyl)-amide]::CHEMBL362684

SMILES: CC(NC(=O)[C@H]1CCC[C@@H]1C(=O)N(C)Cc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1ccc(s1)-c1cccs1

InChI Key: InChIKey=YPYBMHXWZYEIDB-PTOFZMKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50164074 ((1S,2S)-Cyclopentane-1,2-dicarboxylic acid 1-[(1-[...) Show SMILES CC(NC(=O)[C@H]1CCC[C@@H]1C(=O)N(C)Cc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1ccc(s1)-c1cccs1 Show InChI InChI=1S/C31H33N3O4S3/c1-20(26-16-17-28(40-26)27-10-6-18-39-27)33-30(35)24-8-5-9-25(24)31(36)34(2)19-21-12-14-22(15-13-21)23-7-3-4-11-29(23)41(32,37)38/h3-4,6-7,10-18,20,24-25H,5,8-9,19H2,1-2H3,(H,33,35)(H2,32,37,38)/t20?,24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assay				Bioorg Med Chem Lett 15: 1901-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.002 BindingDB Entry DOI: 10.7270/Q2HH6JMD
					More data for this Ligand-Target Pair