BDBM50164077 CHEMBL181256::[PtCl6](2-)::hexachloridoplatinate(2-)hexachloridoplatinate(IV)::hexachloroplatinate(2-)
SMILES: Cl[Pt--](Cl)(Cl)(Cl)(Cl)Cl
InChI Key: InChIKey=GBFHNZZOZWQQPA-UHFFFAOYSA-H
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50164077 (CHEMBL181256 | [PtCl6](2-) | hexachloridoplatinate...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.63E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against human isozymes carbonic anhydrase IX for the CO2 hydration reaction at 20 C | Bioorg Med Chem Lett 15: 1909-13 (2005) Article DOI: 10.1016/j.bmcl.2005.01.082 BindingDB Entry DOI: 10.7270/Q2CR5SWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50164077 (CHEMBL181256 | [PtCl6](2-) | hexachloridoplatinate...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.23E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against human isozymes carbonic anhydrase II for the CO2 hydration reaction at 20 C | Bioorg Med Chem Lett 15: 1909-13 (2005) Article DOI: 10.1016/j.bmcl.2005.01.082 BindingDB Entry DOI: 10.7270/Q2CR5SWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human)) | BDBM50164077 (CHEMBL181256 | [PtCl6](2-) | hexachloridoplatinate...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.08E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against human isozymes carbonic anhydrase V for the CO2 hydration reaction at 20 C | Bioorg Med Chem Lett 15: 1909-13 (2005) Article DOI: 10.1016/j.bmcl.2005.01.082 BindingDB Entry DOI: 10.7270/Q2CR5SWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50164077 (CHEMBL181256 | [PtCl6](2-) | hexachloridoplatinate...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.38E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against human isozyme carbonic anhydrase I for the CO2 hydration reaction at 20 degree C | Bioorg Med Chem Lett 15: 1909-13 (2005) Article DOI: 10.1016/j.bmcl.2005.01.082 BindingDB Entry DOI: 10.7270/Q2CR5SWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM50164077 (CHEMBL181256 | [PtCl6](2-) | hexachloridoplatinate...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.74E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibitory constant against human isozymes carbonic anhydrase IV for the CO2 hydration reaction at 20 degree C | Bioorg Med Chem Lett 15: 1909-13 (2005) Article DOI: 10.1016/j.bmcl.2005.01.082 BindingDB Entry DOI: 10.7270/Q2CR5SWP | |||||||||||
More data for this Ligand-Target Pair |