BDBM50164110 6-(3,5-Dimethoxy-2,6-dimethyl-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL359824

SMILES: COc1cc(OC)c(C)c(c1C)-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O

InChI Key: InChIKey=MOQWMAHAUXPWRX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50164110 (6-(3,5-Dimethoxy-2,6-dimethyl-phenyl)-8-methyl-2-p...) Show SMILES COc1cc(OC)c(C)c(c1C)-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O |(5.67,5.48,;4.32,4.71,;4.36,3.15,;5.7,2.4,;5.7,.86,;7.05,.11,;7.05,-1.45,;4.37,.09,;4.37,-1.45,;3.04,.86,;3.02,2.37,;1.69,3.14,;1.71,.06,;.38,.83,;-.93,.05,;-2.28,.83,;-3.61,.04,;-3.61,-1.5,;-4.94,-2.27,;-6.28,-1.52,;-6.27,.04,;-7.62,.79,;-8.94,.04,;-8.93,-1.52,;-7.6,-2.27,;-2.28,-2.27,;-.93,-1.49,;.4,-2.26,;.4,-3.8,;1.71,-1.49,;3.06,-2.25,)| Show InChI InChI=1S/C24H24N4O3/c1-14-19(30-4)12-20(31-5)15(2)21(14)18-11-16-13-25-24(26-17-9-7-6-8-10-17)27-22(16)28(3)23(18)29/h6-13H,1-5H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of checkpoint kinase Wee1				Bioorg Med Chem Lett 15: 1931-5 (2005) Article DOI: 10.1016/j.bmcl.2005.01.079 BindingDB Entry DOI: 10.7270/Q280524M
					More data for this Ligand-Target Pair