BDBM50164156 6-(2,6-Dichloro-phenyl)-8-methyl-2-{4-[3-(5H-tetrazol-5-yl)-propyl]-phenylamino}-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL178510

SMILES: Cn1c2nc(Nc3ccc(CCCC4N=NN=N4)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key: InChIKey=GHFPJRILDMLFJH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50164156 (6-(2,6-Dichloro-phenyl)-8-methyl-2-{4-[3-(5H-tetra...) Show SMILES Cn1c2nc(Nc3ccc(CCCC4N=NN=N4)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |c:14,16,(3.67,-4.58,;3.67,-3.04,;2.33,-2.27,;.99,-3.04,;-.34,-2.27,;-1.67,-3.06,;-3,-2.29,;-4.33,-3.06,;-5.66,-2.29,;-5.66,-.75,;-7.02,.02,;-7.02,1.56,;-8.35,2.33,;-8.35,3.87,;-7.11,4.78,;-7.58,6.23,;-9.14,6.23,;-9.61,4.76,;-4.33,.02,;-3,-.75,;-.34,-.73,;.99,.04,;2.33,-.73,;3.65,.05,;4.99,-.71,;6.31,.06,;6.31,1.6,;4.95,2.35,;7.63,2.37,;8.97,1.61,;8.98,.09,;7.65,-.71,;7.66,-2.25,;5,-2.26,;6.33,-3.02,)| Show InChI InChI=1S/C24H20Cl2N8O/c1-34-22-15(12-17(23(34)35)21-18(25)5-3-6-19(21)26)13-27-24(29-22)28-16-10-8-14(9-11-16)4-2-7-20-30-32-33-31-20/h3,5-6,8-13,20H,2,4,7H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of checkpoint kinase Wee1				Bioorg Med Chem Lett 15: 1931-5 (2005) Article DOI: 10.1016/j.bmcl.2005.01.079 BindingDB Entry DOI: 10.7270/Q280524M
					More data for this Ligand-Target Pair