BDBM50164157 6-(2,6-Dichloro-3-methyl-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL360689

SMILES: Cc1ccc(Cl)c(c1Cl)-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O

InChI Key: InChIKey=OJVLYJKQBZPGBK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50164157 (6-(2,6-Dichloro-3-methyl-phenyl)-8-methyl-2-phenyl...) Show SMILES Cc1ccc(Cl)c(c1Cl)-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O |(5.05,4.83,;5.05,3.29,;6.4,2.54,;6.4,1,;5.07,.23,;5.09,-1.33,;3.74,.98,;3.74,2.54,;2.39,3.28,;2.41,.23,;1.08,.97,;-.25,.19,;-1.58,.97,;-2.91,.19,;-2.91,-1.34,;-4.24,-2.13,;-5.57,-1.36,;-6.9,-2.13,;-8.23,-1.38,;-8.23,.16,;-6.9,.95,;-5.57,.18,;-1.58,-2.12,;-.25,-1.34,;1.1,-2.12,;1.1,-3.65,;2.43,-1.34,;3.76,-2.08,)| Show InChI InChI=1S/C21H16Cl2N4O/c1-12-8-9-16(22)17(18(12)23)15-10-13-11-24-21(25-14-6-4-3-5-7-14)26-19(13)27(2)20(15)28/h3-11H,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of checkpoint kinase Wee1				Bioorg Med Chem Lett 15: 1931-5 (2005) Article DOI: 10.1016/j.bmcl.2005.01.079 BindingDB Entry DOI: 10.7270/Q280524M
					More data for this Ligand-Target Pair